Aspartame provides food, soft drinks, candy and chewing gum manufacturers with substantial cost savings compared to sugar, which is 200 times less sweet. The history of aspartame dates back to 1965 when the low-calorie sweetener was accidentally discovered by chemist James Schlatter. Dec. 11, 2013 -- The European Food Safety Authority says the artificial sweetener aspartame is safe at the levels currently used in food and drinks. It can also be converted by the body into tyrosine, which is another amino acid used in protein synthesis and for the formation of some hormones and neurotransmitters. The acceptable daily intake limit is set to be about 100 times In addition, the opinion discusses potential uncertainties related mainly to the difficulties associated with using different sources of data, both on consumption and on the levels of aspartame in foods. The EU has set an Acceptable Daily Intake for DKP of 7.5 milligrams per kilogram body weight per day (mg/kg bw/day) to protect consumers against possible harmful effects of this substance in food. Extensive reviews on aspartame have been carried out by many national and international regulatory and advisory bodies. Learn more. has found that the artificial sweetener aspartame is safe for people to consume The body may convert aspartic acid into the neurotransmitter glutamate which at very high levels can have harmful effects on the nervous system. When risk assessors like EFSA establish an ADI for a given substance, their scientific advice informs the decision-making of risk managers regarding the authorisation of specific proposed uses of the substance (i.e. More recent scientific literature and data have been critically analysed and interpreted alongside the information that was first evaluated prior to aspartame’s authorisation. These studies have been critically evaluated and underpin the discussion points addressed in the opinion. The weight of evidence shows that aspartame is not associated with allergic type reactions. Based on exposure levels for aspartame, exposure to DKP from all food and drink using the sweetener would on average be approximately 0.1 to 1.9 mg/kg bw/day for all population groups. As part of its safety evaluations of food additives EFSA establishes, when possible (i.e. Aspartame is a low calorie sugar substitute marketed under brand names like Equal and Nutrasweet. recently launched an aadvertising campaign to dispel fears about Diet Coke after per kilogram body weight. With this approach, by using the weight of evidence from experimental observations and scientific criteria, scientists identify ‘key events’ or ‘biological steps’ which are a sequence of reactions triggered by a chemical in a living organism (e.g. Keywords: Excipients, package leaflet, aspartame, E951, phenylalanine: Description: This document supports the revision of the annex to the European Commission guideline on 'Excipients in the labelling and package leaflet of medicinal products for human use' with regard to aspartame and phenylalanine. Like all food additives, aspartame has been assigned an “E-number” following authorisation. For instance, to reach the ADI for aspartame (40 mg/kg body weight), an adult weighing 60kg would have to drink 12 (330ml) cans of a diet soft drink (containing aspartame at the maximum permitted levels of use), every day for the rest of his/her life. The Panel concluded there is no safety concern for pregnant women at current levels of exposure. For most products containing aspartame, consumption would need to be exceptionally high and regular over a person’s lifetime, in order to exceed the ADI. Aspartame and its breakdown products have been the subject of extensive investigation for more than 30 years including experimental animal studies, clinical research, intake and epidemiological studies and post-marketing surveillance. other studies showed that aspartame might be dangerous, leading to a fall in sales. This is especially critical to the developing fetus in women suffering from PKU. about 3,750 milligrams of aspartame per day for a 165-pound person -- that's about 21 the foods in which it can be used and the maximum proposed levels of use). at the levels currently used in diet soft drinks. It is in this context that EFSA’s Scientific Committee and Scientific Panels carry out safety assessments and review new evidence. The ADI is the amount of a substance that people can consume on a daily basis during their whole life without any appreciable risk to health. “The Panel concluded that aspartame was not of safety The sugar tax may also have something to do with it as they are now replacing the sugar with Aspartame. Since no one wants to be branded with the label, most companies avoid using the dyes. Last year's study that suggested aspartame to be linked to cancer was conducted with rats and this year it has been proven as flawed. No one expert, including the Chair, can unduly influence the decisions of the Panels. Also, while previous safety evaluations of aspartame derived the ADI from long-term toxicity studies in animals, the new risk assessment also uses information from studies in humans. (See Table 18 of the opinion for an overview.). Derived from aspartame is safe for human health degradation products of aspartame has never banned! 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